Nanoparticles are actively employed in medicine as
contrast agents as well as for diagnosis and therapy of various
diseases. However, the development of novel multifunctional
nanoagents is impeded by the difficulty of monitoring their blood
circulation. Researches from the Moscow Institute of Physics and
Technology, the Shemyakin-Ovchinnikov Institute of Bioorganic
Chemistry of RAS, Moscow Engineering Physics Institute, Prokhorov
General Physics Institute of RAS, and Sirius University have
developed a new noninvasive method of nanoparticle measurement in
the bloodstream that boasts a high time resolution. This technique
has revealed the basic parameters that affect particle lifetime in
the bloodstream, which may potentially lead to discovery of new,
more effective nanoagents to be used in biomedicine. The results of
the study have been published in the Journal of Controlled
Release.
