Tailored metal nanoclusters can be actively developed
in the lab to manipulate light at the subwavelength scale for
nanophotonic applications. However, their precise molecular
arrangement in a hotspot with fixed numbers and positions remain
challenging to investigate. Weina Fang and colleagues at the school
of chemistry and chemical engineering, Key Lab of Interfacial
Physics and Technology, Organic Electronics and Information
Displays and the Institute of Intelligent Systems in China and
Germany; engineered DNA origami metamolecules with Fano resonances
(DMFR) (a type of resonance scattering phenomenon), and published
the results in Science Advances. The molecules precisely localized
single dye molecules to produce quantified surface-enhanced Raman
scattering responses (SERS). To deliver tailored plasmonic
combinations, Fang et al. developed a general and programmable
method by anchoring a set of large gold nanoparticles (L-AuNPs) on
prescribed n-tuple (an ordered list of n elements) docking sites of
super-origami DNA frameworks.
Quantizing single-molecule surface enhanced Raman Scattering
with DNA origami metamolecules
