It is currently challenging to directly observe the
formation of intracellular nanostructures in the lab. In a new
report, Miaomiao Zhang and a research team in chemistry, life
sciences, medical engineering and science and technology, in China,
used a rationally designed small molecule abbreviated NBC-Iod-CBT
(short for 4-nitrobenzyl
carbamate–Cys(SEt)-Asp-Asp-Phe(iodine)–2-cyano-benzothiazole) and
directly observed intracellular nanoparticle formation with
nanocomputed tomography (nano-CT).